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Liraglutide and semaglutide are the only GLP-1 RAs currently used, even if not approved, in the treatment of HS [31]
While newer medications like tirzepatide may produce greater early weight loss for some, semaglutide remains a well-established, highly effective option for long-term weight management
On average, patients can lose 10 to 20 percent of their body weight while taking these medications
The Phase 2 trial involved 469 patients who were either obese or overweight
The approval of the pill is based on the OASIS 4 trial, a phase 3 randomised controlled trial published in the New England Journal of Medicine
