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ipamorelin does not, per Raun et al

Contact a doctor if you experience severe nausea and vomiting, diarrhea, paleness of skin, fatigue, dizziness, fainting, unusual bleeding or bruising, blood in the stools, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet

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Helimeds has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations