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The potent weight loss induced by GLP-1MK-801 was linked to a potentiated decrease in food intake in mice treated with GLP-1MK-801 compared to mice treated with vehicle or GLP-1 or MK-801 monotherapies (Fig

In addition, the activation of GLP-1R was shown to promote synaptic plasticity and axonal growth (90)

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Another issue waiting for more studies was the influence between IF and nervous system on obese subjects