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Using human(h) or rat(r) lens epithelial cells (LECs) and aging human lenses, we showed that a progressive increase in oxidative load during aging was linked to a decline in Prdx6 expression
This is because they both slow down stomach emptying
However, the relationship between these mechanisms and our observation that GSH is required to evade polyubiquitylation remains unclear
The gastrointestinal tract and liver degrade a significant portion of ingested GSH before it enters systemic circulation
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