B12 plays a key role in several processes like producing red blood cells, converting food into energy, and producing nerves
When the liver is damaged, however, glutathione production is blocked
References Abd El-Ghafar OA, Hassanein EH, Ali FE, Omar ZM, Rashwan EK, Mohammedsaleh ZM, Sayed AM (2022) Hepatoprotective effect of acetovanillone against methotrexate hepatotoxicity: role of Keap-1/Nrf2/ARE, IL6/STAT-3, and NF-B/AP-1 signaling pathways
Reduce it with therapy, exercise, journaling, and socialization to ease symptoms
Use morning and night, under SPF during the day
Inter-individual variability in homocysteine, due to genetically determined metabolic heterogeneity, will likely become a fruitful area of research