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These efforts have led to the development of various GLP-1 receptor agonists, the most recent being semaglutide and tirzepatide, approved for the treatment of type 2 diabetes in 2018 and 2022, respectively

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Interestingly, recent pilot studies have reported preliminary evidence of potential benefits of acetylcarnitine supplementation alone or as part of a combined dietary intervention in the treatment of long COVID-associated fatigue, energy metabolism alterations and immune changes [93, 110]