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Technique May Also Apply to Other Common Cancers"

Answer: Yes

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Footnote Nonstandard Abbreviations and Acronyms 2-NBDG 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino)-2-deoxyglucose Cas9 clustered regularly interspaced short palindromic repeatassociated 9 CRISPR/Cas9 clustered regularly interspaced short palindromic repeats/clustered regularly interspaced short palindromic repeatassociated 9 DAPI 4,6-diamidino-2-phenylindole DPP-4 dipeptidyl peptidase-4 EC endothelial cell eNOS endothelial NO synthase EPC endothelial progenitor cell FBS fetal bovine serum GLP-1 glucagon-like peptide 1 GLP-1R glucagon-like peptide 1 receptor HG high glucose HLI hind limb ischemia HRP horseradish peroxidase hUCB-EPC human umbilical cord bloodderived EPC HUVEC human umbilical vein endothelial cell INS-1 insulinoma 1 KLF2 Kruppel-like factor 2 LDHA lactate dehydrogenase A mEPC mouse primary bone marrow EPC mBM-EPC mouse bone marrowderived EPC NEP 24.11 neutral endopeptidase 24.11 OCR oxygen consumption rate PAD peripheral artery disease PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 PKA protein kinase A PKG protein kinase G ROS reactive oxygen species T1DM type 1 diabetes UEA-1 ulex europaeus agglutinin-1 WT wild type Supplemental Material File (atvb_atvb-2024-320714d_supp1.pdf) Download 5.37 MB File (atvb_atvb-2024-320714d_supp2.pdf) Download 22.54 MB REFERENCES 1