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Nature 544 (7651), 508
Esto hace que sea fcil de usar en polvo, pero menos conveniente en cpsulas o tabletas porque la porcin puede requerir mltiples unidades grandes
SOD and catalase mimetic compounds naturally exhibit several orders of magnitude lower rate constants than their corresponding enzymes, however, their use in extracellular environments, where concentrations of enzymes are rather low, is of significant importance
It is a fundamentally different approach: instead of trying to force a large peptide through a hostile environment, Lilly designed a small molecule that activates the same receptor through a different structure
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Different mandelic acid concentrations (0.1%, 1%, 2%, and 3%) were tested at pH 4.5, that is at physiological pH
