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Reported signals include prolonged fullness, bloating, or worsening acid reflux after the second compound is added

Normalize plateaus and transitions Metabolic adaptation and hormonal shifts make weight plateaus or partial regain after discontinuation expected, not concerning

[3] Clinical improvement in clinical signs and symptoms following administration of dextrose

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The risk is increased in patients: SGLT2i may need to be withheld or dose reduced in these circumstances

Patients combining GLP-1 therapy with hormone optimization consistently see better body composition outcomes: more fat lost, more muscle retained, better energy throughout the process