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Counterfeit pills could be a bigger medical problem, since they could have different purity, chemical alteration, and increased side effects. In early February, the FDA issued a warning about the distribution and use of compounded GLP-1 medications that are not federally approved

Two studies 14,21 were identified that evaluated the effect of GLP-1-based therapies in a controlled longitudinal design

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Therefore, while CTSB inhibition appears to reduce trypsin activation and mitigate disease severity, modulating CTSL activity may not confer similar therapeutic benefits