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This is supported by cell-killing assays which indicate increased lysis of NK cell-sensitive lines after GLP-1 treatment, alongside heightened production of IFN- and granzyme B [173]

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The sustained GH elevation from DAC can increase side effects including water retention and insulin resistance

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Detailed information is shown in each figure legend

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Acknowledgements K.A

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Other safety considerations include: Common gastrointestinal side effects (nausea, vomiting, diarrhoea), which can affect absorption of oral medications, including levothyroxine [1] [7] Risk of pancreatitisseek urgent medical attention if you develop severe, persistent abdominal pain Gallbladder problems, including gallstones Potential worsening of diabetic retinopathy in people with type 2 diabetes If you experience severe or persistent side effects, contact your healthcare provider, as this may necessitate temporary dose adjustment or interruption of Wegovy

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Availability and costs are a key factor in the possibility of generalized implementation of these systems

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