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The peptide is constructed on a GIP receptor backbone with non-coded amino acid residues (Aib2, Aib20, aMeL13) and a C20 fatty diacid moiety that enables albumin binding, extending pharmacokinetic half-life for once-weekly administration in research settings

no large-scale controlled human clinical trials establishing safety or efficacy currently exist

They also found that lower body stores are correlated with higher absorption rates

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A faint blue-green tint at the injection site is sometimes reported and is associated with the copper in GHK-Cu (cosmetic only)