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The message is clear: weight loss itself is a meaningful therapeutic lever in obese PsA patients, complicating any attempt to attribute GLP-1RA benefits to drug-specific mechanisms

By converting superoxide into hydrogen peroxide that is further cleared by catalase and glutathione peroxidase, SOD preserves glutathione levels, reduces inflammatory stress, and activates Nrf2 signaling, which upregulates the bodys primary detox enzymes

Now, she is going back to Wegovy

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Weight loss entirely due to fat reduction

Heerspink expressed optimism about future investigations, stating, All signals are green to test this drug in a larger study