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11 KPV Anti-Inflammatory Activity (PubMed)KPV reduces inflammation in cell and colitis models via NF-B pathway modulation

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It dramatically reduces activity of the sebaceous glands, normalises skin cell shedding, and decreases C

Barnes J, Anderson LA, Phillipson JD

A major role of the mitochondrial malic enzymes, which includes the NAD(H)-dependent ME2 enzyme, is principally to provide the cell with an alternate source of pyruvate under conditions where glycolytic flux in reduced

However, it is not approved for human use by the FDA and is banned in competitive sports by WADA