Women should communicate with their healthcare provider to adjust dosing if side effects persist
For most patients, these symptoms are mild to moderate, peak during the escalation phase, and gradually fade as tolerance develops
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Go to the emergency room or call 911 (or your local emergency services number)
reported that CB-839 could promote the production of reactive oxygen species (ROS) in colorectal cancer cells, cause nuclear translocation of Nrf2, and subsequently upregulate the expression of uridine phosphorylase 1 (UPP1), which promotes the activation of 5-fluorouracil (5-FU)