Giving a smaller dose of Ozempic or any other GLP-1 can still produce these side effects such as nausea, vomiting, muscle loss, upset stomach, headaches, and slowing of bowel movements potentially leading to ileus or obstruction. George said that microdoses of the drug are only as safe as the pharmacy producing it: To access these custom doses, Noom must use a specialized compounding pharmacy
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Primary outcomes were changes in HbA 1c and body weight from baseline
Why consider microdosing
Patients experiencing significant hair shedding should discuss this with their prescribing clinician, who may recommend blood tests to exclude nutritional deficiencies (iron, B12, folate, zinc) or thyroid dysfunction as contributing factors
The letter creates a clear national roadmap for enforcement and signals that state and federal regulators may soon coordinate efforts to curb GLP-1 misconduct