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Compound 968 can inhibit the activity of GLS2 and overcome the resistance of cancer cells to selective GLS1 inhibitors, resulting in tumor suppression (Lukey et al., 2019)
Hynos 23
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Research reveals that senescent cells show upregulation of pro-apoptotic initiators PUMA and BIM while anti-apoptotic guardian BCL-2 is reduced, suggesting these cells are ready to undergo apoptosis but the execution is restrained by the FOXO4-p53 interaction
It cannot confirm sterility
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