diarrhea on tirzepatide (Mounjaro) affects approximately 23–31% of patients and is typically mild to moderate, transient, and most common during dose escalation. , It rarely requires discontinuation Why Does Tirzepatide Cause Diarrhea?

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Kong Y, Peng Q, Lv N, Yuan J, Deng Z, Liang X, et al

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However, even with official approval, access remained limited by high pharmaceutical prices, insurance coverage gaps, and production shortages that persisted for years after launch