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Post-treatment, the expression of the serotonin reuptake transporter (SERT) significantly increased, while tryptophan hydroxylase-1 (TPH-1) expression significantly decreased in colonic tissue, suggesting exendin-4 mitigates visceral hypersensitivity by upregulating SERT and downregulating TPH-1

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Once they have narrowed down the root cause(s), they can begin teaching the patient the foundational elements of their health, such as proper nutrition, the importance of movement and adequate sleep, how to manage their stress levels, and detoxification

PMCID: PMC5817971

Aim This review aims to provide an integrated synthesis that bridges mechanistic evidence (anti-inflammatory, antioxidant) with clinical outcomes (mortality, arrhythmias) for LC supplementation in CAD, while critically appraising inconsistencies across the literature (e.g., heart failure, reinfarction)

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