compounding glp 1 FDA says that the GLP-1 shortage is over Navigating GLP-1 Compounding: FDA and

The amino acid sequence and modifications in its chemical structure enable it to selectively stimulate the release of growth hormone, while avoiding some adverse reactions that traditional drugs may cause

Arnold AC

Additionally, the administration of oral GLP-1 drugs requires strict guidelines: for example, semaglutide must be taken on an empty stomach in the morning, with no more than 120 mL of water, and followed by at least 30 minutes of waiting before breakfast

& Bankir, L

Chip 13 , 32533260 (2013)

studies have shown a 0.6% A1C decrease after approximately 6 months of sitagliptin or alogliptin therapy, compared with 0.5% for saxagliptin and 0.4% for linagliptin