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For B12 to be absorbed, it requires a protein called intrinsic factor (IF)

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For semaglutide, one could expect a different side-effect profile for the oral versus the subcutaneous formulation

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doi: 10.1111/j.1440-1754.2007.01267.x, 10 BorrellL

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Following MP phagocytosis, immune cells obstructed cortical capillaries, producing neurological deficits that persisted for 4 weeks (Huang et al., 2025)

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In another study conducted in mice with Alzheimer disease in the final stage, intraperitoneal liraglutide improved spatial memory, reduced amyloid deposition and inflammation, and increased dentate gyrus neurogenesis, suggesting that, besides exerting preventive effects, this GLP-1RA may reverse some of the key pathological findings of Alzheimer disease

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