Abbreviations CKD: Chronic kidney disease DKA: Diabetic ketoacidosis FDA: US Food and Drug Administration GLP-1 RA: Glucagon-like peptide-1 receptor agonist HCO: Healthcare organisation IHD: Ischaemic heart disease PSM: Propensity score matching SGLT2i: Sodium-glucose cotransporter 2 inhibitor SSMD: Strictly standardised mean difference UTI: Urinary tract infection References Gregory GA, Robinson TIG, Linklater SE et al (2022) Global incidence, prevalence, and mortality of type 1 diabetes in 2021 with projection to 2040: a modelling study
Headaches, nausea, kidney stones, asthma attacks in individuals with asthma, abdominal pain, chest tightness, and even kidney failure have also been reported as possible side effects
Since GLP-1R is a target in diabetes mellitus, it enhances the proliferation of -cells and insulin secretion in the pancreas and reduces plasma glucose levels [60, 61]
Scaglia F, Sutton VR, Bodamer OA, Vogel H, Shapira SK, Naviaux RK, Vladutiu GD
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(PMID: 15531385), rats given BPC-157 0.0045 mg/lb showed significantly elevated serotonin synthesis in the substantia nigra reticulata and medial anterior olfactory nucleus following acute administration
