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Medication is likely long-term or indefinite, and weight regain may occur upon discontinuation
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Research indicates that the reduced glycemic variability achieved with pramlintide may independently lower cardiovascular risk, as glucose fluctuations have been associated with endothelial dysfunction and increased oxidative stress
This is why poorly vascularized tissues like tendons heal slowly, and why conditions that impair angiogenesis (like diabetes) cause chronic wounds
Not for use in children
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