Our Physical Medicine branch, overseen by our Medical Director, Dr
Trina Wilcox: So, they all started out treating specifically diabetes, is that correct

Abbreviations AACE/ACE: American Association of Clinical Endocrinologists/American College of Endocrinology ADA: American Diabetes Association ASCVD: Atherosclerotic cardiovascular disease AUC: Area under the curve C avg : Average plasma concentration CI: Confidence interval C max : Maximum concentration CV: Cardiovascular CVD: Cardiovascular disease CVOT: Cardiovascular outcomes trial DPP-4: Dipeptidyl peptidase-4 empa: empagliflozin ETD: Estimated treatment difference FDA: Food and Drug Administration GI: Gastrointestinal GLP-1: Glucagon-like peptide-1 GLP-1RA: Glucagon-like peptide-1 receptor agonist GRAS: Generally regarded as safe HbA 1c : Glycated hemoglobin HR: Hazard ratio imp.: impairment lira: liraglutide MACE: Major adverse cardiovascular events met: metformin OAD: Oral antidiabetes drug pbo: placebo s.c.: subcutaneous sema: semaglutide SGLT2i: Sodium-glucose co-transporter-2 inhibitor sita: sitagliptin SNAC: Sodium N-(8-[2-hydroxybenzoyl]amino)caprylate SU: Sulfonylurea t 1/2 : Terminal half-life T2D: Type 2 diabetes T max : Time to maximum concentration References Lau JL, Dunn MK

12-Month Total Cost Comparison To illustrate the long-term cost implications, let us calculate the approximate total 12-month cost for a patient who follows the standard titration schedule: 0.25 mg for months 1-2, 0.5 mg for months 3-4, 1.0 mg for months 5-6, and a maintenance dose of 1.7 mg for months 7-12
[17] [18] Proton pump inhibitors (PPIs) : If GORD is contributing, a PPI such as omeprazole 20 mg once daily may provide benefit
Therefore, it demonstrates significant efficacy in weight loss, blood sugar control, and cardiovascular protection, making it an important treatment option for type 2 diabetes patients and individuals managing their weight