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NNMT enzyme inhibition occurs within 24 hours of subcutaneous dosing based on pharmacokinetic modelling, but downstream metabolic effects NAD+ elevation, changes in fat oxidation markers typically require 24 weeks of consistent dosing to manifest in measurable endpoints

Current research shows that AOD9604 is exceptionally safe

PMC 7653199

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Each mL of the solution contains 1,000 mcg of cyanocobalamin