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That matters because glucagon activation increases your baseline calorie burn and enhances fat breakdown through heat production, basically adding a metabolic accelerator that semaglutide and tirzepatide lack entirely

Tirzepatide versus semaglutide for men The head-to-head data is now available

doi: 10.1016/j.foodchem.2014.07.147 4 EswayahA

doi: 10.1016/j.clinthera.2011.11.024

This can be measured using a wattmeter, ESC data logger or current sensor