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Acknowledgements We thank Dr David Blum, Dr Stphane Dalle and Dr Benoit Pourcet and members of the INSERM U1283/CNRS UMR 8199/EGID for helpful discussions and critical reading of our manuscript

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OTHER INGREDIENTS: Deionised Water, L-Carnitine, Malic Acid, Green Tea Extract, Vitamin C, Sweeteners (Sucralose), Natural Flavoring, Preservatives (Potassium Sorbate, Sodium Benzoate), Colour (Caramel Extract)

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In particular, since the pivotal role of inflammation in COVID-19 life threatening complications had been identified shortly after the outbreak in Wuhan, particular attention should have been paid to identify the most active and appropriate anti-inflammatory medications, and recommend their prescription at the presentation of the early symptoms to prevent their progression (Sestili and Stocchi, 2020)