Compared with the rapid translocation of Nrf2 induced by DEM, NFT treatment resulted in a rather slow, but constant rise in the intensity of nuclear Nrf2 signals (Fig
Significant SOCs for which at least one of the four methods of disproportionality analysis met the criteria were injury, poisoning and procedural complications (SOC code: 10000044), general disorders and administration site conditions (SOC code: 10017581), gastrointestinal disorders (SOC code: 10000050), and metabolism and nutrition disorders (SOC code: 10065941)
Safety data published so far list gastrointestinal effects as the dominant adverse events and record only small numbers of thrombotic events without a reproducible pattern across trials
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