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Illustratively, BPC 157 may interfere with NO-system activities (Sikiric et al., 2014) and counteract harmful events, arising from either NO-blockade (L-NAME-application) or L-arginine (NOS-substrate-application) (Sikiric et al., 2014)

So, with too much oxidative stress and not enough antioxidants to counteract it, we get into a vicious cycle of oxidative stress, inflammation, and ill-health

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Reduce the dose by 50% or switch to twice-daily split dosing (e.g., 25mg morning and 25mg evening instead of 50mg once daily)

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