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One can induce a Parkinsons-like condition in rats by injecting a poison in their right medial forebrain bundle (Nurrahma et al., 2021)

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This is clearly demonstrated in people living with DS, where the overexpression of CBS is a genetic consequence that causes a significant reduction of serum homocysteine concentration leading to less available methionine within the methionine cycle

PMID 3085206

Subsequently, the cells were washed with PBS and observed under a fluorescence microscope (Nikon, Tokyo, Japan)

Polaris is worth evaluating for the multi-lab approach, particularly for researchers who already hold an account