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Tirzepatide, the dual GLP-1/GIP agonist marketed as Zepbound for obesity and Mounjaro for type 2 diabetes, is currently the most potent approved agent in the class

Interestingly, an increased fat mass was once considered to confer protection for bone health (137, 138)

The SURMOUNT-5 head-to-head trial confirmed tirzepatide outperforms semaglutide by approximately 6 percentage points on average weight loss

Deep venous thrombosis (TVP): clots that are usually formed on the legs

A systematic approach to diagnosis of mature T-cell leukemias reveals heterogeneity among WHO categories

However, published data on this specific combination remains limited