Concentrations above 500mcg/mL compress dose volumes below 10 units, where measurement precision drops
Biguanides also interacts with REDD1, (Luengo et al., 2017), IRS receptors, (Luengo et al., 2017), glucose metabolism, (Luengo et al., 2017
In addition, gamete transfer is inhibited due to impedance of tubal motility due to elevated levels of cytokines (31)
When paired with TRT, the synergy can lead to improved body composition , better energy levels, and sustainable fat loss
Generally, it can be used with other medications, but its best to consult your doctor to avoid any potential interactions or contraindications
Women prescribed GLP-1 medications for licensed indications who also experience menopausal symptoms should discuss their full symptom profile with their healthcare provider