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The increase in the incidence of cancer, diabetes, cardiovascular disease, and psychiatric disorders (7072), might also be related to disruption of sleep-wake rhythms, impaired secretion of melatonin from nighttime light, combined with obesity and a tendency to produce reactive oxygen species (73), which also affects the circadian rhythm of GLP-1 secretion
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Then, through the catalytic action of GR, GSSG is reduced back to GSH, achieving its regeneration and sustained antioxidant effect
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