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Semaglutide works by mimicking GLP-1, a hormone that helps control blood sugar levels by causing the pancreas to release insulin, decreasing the production of glucagon, and slowing down the emptying of the stomach
In a nutshell: No
If large swathes of the general public start taking them off-label for weight loss and then we find out years later that there are bad side effects, it could be a real issue. Rethinking long-term weight management strategies to overcome cost barriers Yet another dimension affecting the use of GLP-1RAs is cost
Bissonnette 2023)
Wegovy and Zepbound moved GLP-1 therapy into chronic weight management, creating a direct challenge to older anti-obesity drugs that often delivered limited efficacy or poor tolerability
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