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For instance, treating the nasolabial folds (smile lines) may require a full syringe of filler, while treating the cheeks may require two syringes
This is also the point at which comparing your day-1 baseline photo to a current photo, taken in the same lighting and angle, tends to show the most striking difference which is precisely why taking that baseline photo on day one (not week 4 or 6) matters, as discussed above
For understanding the mechanism and how it relates to dosing, see mechanism of action
doi:10.1111/j.1600-079x.2005.00265.x
Most compelling evidence is from animal models
J Pediatr 138:880887
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