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The second subgroup comprised trials where ALC was given in combination with another antidepressant, compared with the same concomitant therapy, either with or without placebo (n=3)

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Among patients without CKD, minimal increases in serum creatinine were observed for patients on a GLP-1 compared to those who were not prescribed a GLP-1: 0.01 mg/dL for semaglutide, 0.01 mg/dL for liraglutide, and 0.02 mg/dL for tirzepatide

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