GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) mimic this hormone to slow gastric emptying, reducing appetite and curbing food cravings
Among the emerging areas of interest are therapies originally developed for metabolic disease that appear to influence multiple aging-related pathways
All four work together
In vivo data were analysed with a two-way ANOVA followed by Tukeys post-hoc test (fasted glucose levels, ipGTT glucose excursion, body weight and food intake) or a one-way ANOVA followed by Dunnetts or Tukeys post-hoc test (glucose AUC, terminal fat and clinical chemistry data)
supervised exercise can strengthen periarticular muscles and reduce joint loading Topical NSAIDs (e.g., topical diclofenac) as a preferred first-line pharmacological option for localised joint pain, particularly in older adults where systemic NSAID use carries greater risk Paracetamol is not routinely recommended by NICE for osteoarthritis-type pain but may be considered for short-term use if other options are unsuitable or not tolerated [15] [16] Cold or warm compresses for symptomatic relief If oral NSAIDs are considered necessary, they should be used at the lowest effective dose for the shortest possible duration, on medical advice, and with gastroprotection (a proton pump inhibitor) as recommended by NICE
Platforms entering the market must work within strict data-protection, medical-practice and reimbursement requirements