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Plioplys AV et al
C ommon causes of plateaus while using GLP-1s Weight loss plateaus can be frustrating
Chronic neuroinflammation, oxidative stress, and impaired glucose metabolism in the brain are also recognized as contributing factors to disease pathogenesis
Symptoms like hair loss, fatigue, flaky skin, or bruising, muscle weakness, poor wound healing may indicate insufficiency (Mozafariun et al 2025)
If you're experiencing purging, the counterintuitive solution is often to continue use
Author Correction: Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial
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