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Takahashi H, Nomiyama T, Terawaki Y, Kawanami T, Hamaguchi Y, Tanaka T, Tanabe M, Bruemmer D, Yanase T

This may seems paradoxical at first, but we must consider that ROS may have several potential roles in physiology

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15 Additionally, a literature review reported that resveratrol may have dose-related adverse effects, possible cytochrome P450 interactions, and potential interaction with drugs such as warfarin, which could increase bleeding risk

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This combination resolves constipation in about 70% of affected patients within 2-3 weeks