Ozempic is approved for type 2 diabetes (0.25 mg to 2 mg), while Wegovy is approved for chronic weight management (up to 2.4 mg) and to reduce the risk of major adverse cardiovascular events in adults with established cardiovascular disease and either overweight or obesity Exenatide extended-release (Bydureon BCise) : Once-weekly injection using microsphere technology Liraglutide (Victoza, Saxenda) : Once-daily injection
Stopping seven days prior was a risk factor for aspiration pneumonitis (odds ratio, 1.29), with higher risks seen for stopping five days and one day prior (odds ratios, 2.74 and 2.74, respectively)
If your provider recommends weaning or reducing feeds If weaning becomes part of your care plan, gradual reduction is often more comfortable than stopping suddenly when that is possible
doi: 10.1016/j.bbadis.2013.01.008 50 DumanR
13 Two meta-analyses of other GLP-1 RA CVOTs found that GLP-1 RAs were associated with greater rates of DR progression, but both studies found that the effect was driven by the extent of hemoglobin A1c reduction, rather than the medications themselves
Some key messages and common themes emerge