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Specifically, GLP-1 receptor activation stimulates the production of cAMP, thereby promoting glucose-dependent insulin secretion by pancreatic -cells, inhibiting glucagon secretion by -cells, delaying gastric emptying, and suppressing the hypothalamic appetite center, resulting in glucose-lowering and weight-loss effects (Nauck et al., 2021
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Ipamorelin is primarily administered via subcutaneous injections in the stomach or abdomen
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