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doi: 10.1016/S0140-6736(21)01751-7
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In addition to blunted monoaminergic neurotransmission, it was also shown that deficiency in neurotrophic factor effects, disturbances in neurogenesis and synaptogenesis, chronic neuroinflammatory processes, and dysregulation of the hypothalamicpituitaryadrenal (HPA) axis can largely contribute to the manifestation of depressive symptoms in patients [3,4,5]
The recommended dosage of L carnitine supplementation is a maximum of 2g per day, with most people finding 4.5mg is enough to feel the full benefit
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