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The Therapeutic Goods Administration (TGA) says that because suicidal behaviour and ideation have been reported with these relatively new GLP-1 receptor agonists, doctors should monitor patients for the emergence or worsening of depression, suicidal thoughts or behaviours, and/or any unusual changes in mood or behaviour

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Importantly, we highlight recent evidence on colonic microbial metabolites of EC, which exhibit diverse and sometimes enhanced bioactivities compared to the parent compound