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FDX1 and LIAS, two key regulators of cuproptosis, are consistently upregulated in bulk RNA-seq, single-cell RNA sequencing, and spatial transcriptomics analyses in human samples (216)

All these functions are mediated by a group of carnitine acyltransferases, enzymes specific for the acyl- chain lenghts

In animal models of hind limb ischemia, the peptide accelerates blood flow recovery and increases vessel number, confirming functional angiogenic capacity

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For example, research suggests BPC-157 may balance nitric oxide levels, which influence blood flow and inflammation

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