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John Buse, MD, PhD, director of the Diabetes Center at the University of North Carolina Chapel Hill, told Verywell that in general, taking a pause from such medications when youre on vacation is a particularly bad idea. Buse explains that for people who are prescribed these drugs for medical reasons, like for type 2 diabetes management or weight loss, following the medication guidelines is very important

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The recommended 4-week minimum at each dose level exists because the body needs time to adjust