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Oral mucosal and epidermal melanocytes are histologically and ultrastructurally similar, but under physiological conditions, it seems that the former are intrinsically less metabolically active

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Eng identified exendin-4 and published the finding in 1992

49 Melanomas most often occur after puberty and tend to arise at the dermal-epidermal junction, in contrast to the earlier onset and deeper origin of many melanomas arising within large CMN