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In very rare cases, extremely high doses have been linked to more significant issues like respiratory sensitivity or a drop in zinc levels over time

Thus, an increase in NRF2 activity, reflected by induction of NRF2 target genes, likely represent an important mechanism mediating the protection seen in GCLM KO mice

However, some evidence suggests mechanisms involving glucose and insulin control, reducing body weight and BP, and improving blood lipid profiles [35]

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Allergy Immunol