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We also investigated the behavior of GSH(t) during the menstrual cycle, and showed that GSH remains stable during the menstrual cycle, which was completely unexpected given the wide range of GSH steady states seen in Figure 2

PMCID: PMC1319235

The dermal papilla cell experiments confirmed the mechanism

These studies indicate the potential of utilizing the de novo pathway, a less extensively studied pathway, as a therapeutic strategy for metabolic diseases Barth syndrome is a rare disease caused by mutations in the tafazzin gene encoding for cardiolipin (CL), a phospholipid specific for the mitochondria 303

On the other hand, depression is characterized by a significantly decreased antioxidant status that potentially leads to impaired protection against oxidative stress (7)

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