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Studies show that GLP-1 medications can affect reproductive hormones in women with obesity and polycystic ovary syndrome (PCOS)

Although epiploic appendagitis has not been identified as an adverse event signal in randomized trials, systematic reviews, or pharmacovigilance reports of GLP-1/GIP receptor agonists, this observation highlights a biologically plausible temporal relationship that may be related to abrupt changes in visceral adipose tissue and regional perfusion

Taking two doses to reach 3mg exceeds the safety limits established in clinical trials

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Duration: Typically continued for several weeks to months, depending on patient response