PGN has been shown to induce GI lesions, and tumors, and to induce a severe inflammatory response in the GI tract of most laboratory animals
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A concussion, for example, can cause a leaky blood-brain barrier, which then causes leakage in the intestinal barrier
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Furthermore, a comprehensive review published in the Journal of Translational Medicine proposed a unifying model for ME/CFS and Long COVID, highlighting how viral infections (like SARS-CoV-2 or Epstein-Barr Virus) trigger a cascade of immune exhaustion, micro-clotting, and severe oxidative stress
For clinical trial participants and healthcare professionals: always follow the storage instructions on the IMP label and those provided by the trial site pharmacist